By Wilson Golder N.
Provides clinical scholars 500 questions, solutions, and factors to organize for the biochemistry and genetics sections of the USMLE Step 1. the hot variation comprises many new questions within the two-step medical structure to simulate the USMLE Step 1.
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Even supposing the professional compendia outline a drug substance as to identification, purity, power, and caliber, they quite often don't offer different actual or chemical facts, nor do they record equipment of synthesis or pathways of actual or organic degradation and metabolism. Such info is scattered in the course of the medical literature and the documents of pharmaceutical laboratories.
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D. e. Golgi apparatus Smooth endoplasmic reticulum Free polysomes Nucleus Rough endoplasmic reticulum 56. Which of the following statements regarding eukaryotic cells is true? a. b. c. d. e. Formylated methionyl-tRNA is important for initiation of translation Single mRNAs specify more than one gene product Cycloheximide blocks elongation during translation Cytosolic ribosomes are smaller than those found in prokaryotes Erythromycin inhibits elongation during translation 57. Modification of mRNA so that a signal sequence is added to the amino terminus of the cytosolic protein, α-globin, results in a.
B. c. d. e. The 3′ end is phosphorylated They are duplex chains No methylated bases are found The anticodon loop is identical The 3′ end base sequence is CCA 68. Methionyl–transfer (t) RNA is used for initiation of protein synthesis by which of the following? a. b. c. d. e. Chloroplast ribosomes Eukaryotic mitochondrial ribosomes Eukaryotic cytoplasmic ribosomes Bacterial ribosomes Bacterial cytoplasm 69. Which of the following is required for certain types of eukaryotic protein synthesis but not for prokaryotic protein synthesis?
Reverse transcriptase is an RNA-dependent DNA polymerase that can synthesize first a single strand and then a doublestranded DNA from a single-strand RNA template. It was originally found in animal retroviruses. Primase is a DNA-dependent RNA polymerase enzyme that synthesizes an RNA molecule 10 to 200 nucleotides in length that initiates or “primes” DNA synthesis. DNA ligase joins DNA fragments and DNA gyrase winds or unwinds DNA. Transfer RNA, 5SRNA, and other small RNAs are synthesized by RNA polymerase III (RNA polymerase I synthesizes ribosomal RNA and RNA polymerase II synthesizes messenger RNA).
AHFS Drug Information 2004 by Wilson Golder N.